Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes

Recent hypotheses propose that the human placenta and chorioamniotic membranes (CAMs) experience telomere length (TL)-mediated senescence. These hypotheses are based on mean TL (mTL) measurements, but replicative senescence is triggered by short and dysfunctional telomeres, not mTL. We measured shor...

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Detalles Bibliográficos
Autores principales: Lai, Tsung-Po, Simpson, Mark, Patel, Krunal, Verhulst, Simon, Noh, Jungsik, Roche, Natalie, Heller, Debra, Guirguis, George, Shay, Jerry W., Herbig, Utz, Aviv, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933277/
https://www.ncbi.nlm.nih.gov/pubmed/33664422
http://dx.doi.org/10.1038/s41598-021-84728-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933277/
https://www.ncbi.nlm.nih.gov/pubmed/33664422
http://dx.doi.org/10.1038/s41598-021-84728-2

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