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Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes
Recent hypotheses propose that the human placenta and chorioamniotic membranes (CAMs) experience telomere length (TL)-mediated senescence. These hypotheses are based on mean TL (mTL) measurements, but replicative senescence is triggered by short and dysfunctional telomeres, not mTL. We measured shor...
Autores principales: | Lai, Tsung-Po, Simpson, Mark, Patel, Krunal, Verhulst, Simon, Noh, Jungsik, Roche, Natalie, Heller, Debra, Guirguis, George, Shay, Jerry W., Herbig, Utz, Aviv, Abraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933277/ https://www.ncbi.nlm.nih.gov/pubmed/33664422 http://dx.doi.org/10.1038/s41598-021-84728-2 |
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