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A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors

Biosensors are key components in engineered biological systems, providing a means of measuring and acting upon the large biochemical space in living cells. However, generating small molecule sensing elements and integrating them into in vivo biosensors have been challenging. Here, using aptamer-coup...

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Detalles Bibliográficos
Autores principales: Townshend, Brent, Xiang, Joy S., Manzanarez, Gabriel, Hayden, Eric J., Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933316/
https://www.ncbi.nlm.nih.gov/pubmed/33664255
http://dx.doi.org/10.1038/s41467-021-21716-0