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A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors
Biosensors are key components in engineered biological systems, providing a means of measuring and acting upon the large biochemical space in living cells. However, generating small molecule sensing elements and integrating them into in vivo biosensors have been challenging. Here, using aptamer-coup...
Autores principales: | Townshend, Brent, Xiang, Joy S., Manzanarez, Gabriel, Hayden, Eric J., Smolke, Christina D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933316/ https://www.ncbi.nlm.nih.gov/pubmed/33664255 http://dx.doi.org/10.1038/s41467-021-21716-0 |
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