SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer

Alternative splicing is a critical process to generate protein diversity. However, whether and how alternative splicing regulates autophagy remains largely elusive. Here we systematically identify the splicing factor SRSF1 as an autophagy suppressor. Specifically, SRSF1 inhibits autophagosome format...

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Detalles Bibliográficos
Autores principales: Lv, Yuesheng, Zhang, Wenjing, Zhao, Jinyao, Sun, Bing, Qi, Yangfan, Ji, Haoyu, Chen, Chaoqun, Zhang, Jinrui, Sheng, Junxiu, Wang, Taishu, Dominguez, Daniel, Liu, Han, Liu, Quentin, Meng, Songshu, Li, Xiaoling, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933324/
https://www.ncbi.nlm.nih.gov/pubmed/33664238
http://dx.doi.org/10.1038/s41392-021-00495-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933324/
https://www.ncbi.nlm.nih.gov/pubmed/33664238
http://dx.doi.org/10.1038/s41392-021-00495-6

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