The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain

Heterogeneous ribonucleoproteins (hnRNPs) are RNA binding molecules that are involved in key processes such as RNA splicing and transcription. One such hnRNP protein, hnRNP L, regulates alternative splicing (AS) by binding to pre-mRNA transcripts. However, it is unclear what factors contribute to hn...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Saikat, Levy, Michaella J., Zhang, Ning, Li, Hua, Florens, Laurence, Washburn, Michael P., Workman, Jerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933334/
https://www.ncbi.nlm.nih.gov/pubmed/33664260
http://dx.doi.org/10.1038/s41467-021-21663-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933334/
https://www.ncbi.nlm.nih.gov/pubmed/33664260
http://dx.doi.org/10.1038/s41467-021-21663-w

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