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The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain
Heterogeneous ribonucleoproteins (hnRNPs) are RNA binding molecules that are involved in key processes such as RNA splicing and transcription. One such hnRNP protein, hnRNP L, regulates alternative splicing (AS) by binding to pre-mRNA transcripts. However, it is unclear what factors contribute to hn...
Autores principales: | Bhattacharya, Saikat, Levy, Michaella J., Zhang, Ning, Li, Hua, Florens, Laurence, Washburn, Michael P., Workman, Jerry L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933334/ https://www.ncbi.nlm.nih.gov/pubmed/33664260 http://dx.doi.org/10.1038/s41467-021-21663-w |
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