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Aberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects

Wnt signaling plays a major role in early neural development. An aberrant activation in Wnt/β-catenin pathway causes defective anteroposterior patterning, which results in neural tube closure defects (NTDs). Changes in folate metabolism may participate in early embryo fate determination. We have ide...

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Detalles Bibliográficos
Autores principales: Li, Jianting, Xie, Qiu, Gao, Jun, Wang, Fang, Bao, Yihua, Wu, Lihua, Yang, Lihong, Liu, Zhizhen, Guo, Rui, Khan, Ajab, Dan Liu, Li, Caihua, Wu, Jianxin, Xie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933360/
https://www.ncbi.nlm.nih.gov/pubmed/33664222
http://dx.doi.org/10.1038/s41419-020-03313-z