Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

The cerebrospinal fluid (CSF) real-time quaking-induced conversion assay (RT-QuIC) is an ultrasensitive prion amyloid seeding assay for diagnosis of sporadic Creutzfeldt–Jakob disease (CJD) but several prion strains remain unexplored or resistant to conversion with commonly used recombinant prion pr...

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Detalles Bibliográficos
Autores principales: Mok, Tze How, Nihat, Akin, Luk, Connie, Sequeira, Danielle, Batchelor, Mark, Mead, Simon, Collinge, John, Jackson, Graham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933407/
https://www.ncbi.nlm.nih.gov/pubmed/33664355
http://dx.doi.org/10.1038/s41598-021-84527-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933407/
https://www.ncbi.nlm.nih.gov/pubmed/33664355
http://dx.doi.org/10.1038/s41598-021-84527-9

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