Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia

The infiltration of chronic lymphocytic leukemia (CLL) cells into lymphoid organs correlates with disease severity. CXCL12 is a key chemotactic factor for the trafficking of CLL. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor and plays a role in CXCL12-mediated hematopoietic s...

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Detalles Bibliográficos
Autores principales: Cui, Xue Yan, Tjønnfjord, Geir Erland, Kanse, Sandip M., Dahm, Anders Erik Astrup, Iversen, Nina, Myklebust, Christiane Filion, Sun, Ling, Jiang, Zhong Xing, Ueland, Thor, Campbell, James J., Ho, Mitchell, Sandset, Per Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933411/
https://www.ncbi.nlm.nih.gov/pubmed/33664415
http://dx.doi.org/10.1038/s41598-021-84695-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933411/
https://www.ncbi.nlm.nih.gov/pubmed/33664415
http://dx.doi.org/10.1038/s41598-021-84695-8

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