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Cellular Metabolites Regulate Central Nucleic Acid Sensing Pathways

Detection of pathogen-derived DNA or RNA species by cellular nucleic acid sensors prompts release of anti-microbial interferons and cytokines. In contrast to their protective anti-microbial functions, inappropriate or excessive activation of nucleic acid sensors can cause inflammatory diseases. Nucl...

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Detalles Bibliográficos
Autores principales: Blay-Cadanet, Julia, Pedersen, Alice, Holm, Christian Kanstrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933466/
https://www.ncbi.nlm.nih.gov/pubmed/33679790
http://dx.doi.org/10.3389/fimmu.2021.635738