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Phenotypic Characterization and Brain Structure Analysis of Calcium Channel Subunit α(2)δ-2 Mutant (Ducky) and α(2)δ Double Knockout Mice
Auxiliary α(2)δ subunits of voltage-gated calcium channels modulate channel trafficking, current properties, and synapse formation. Three of the four isoforms (α(2)δ-1, α(2)δ-2, and α(2)δ-3) are abundantly expressed in the brain; however, of the available knockout models, only α(2)δ-2 knockout or mu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933509/ https://www.ncbi.nlm.nih.gov/pubmed/33679366 http://dx.doi.org/10.3389/fnsyn.2021.634412 |