P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl)ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease

Huntington’s disease (HD) is a life-threatening neurodegenerative disorder. Altered levels and functions of the purinergic ionotropic P2X7 receptors (P2X7Rs) have been found in animal and cellular models of HD, suggesting their possible role in the pathogenesis of the disease; accordingly, the thera...

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Detalles Bibliográficos
Autores principales: Martire, Alberto, Pepponi, Rita, Liguori, Francesco, Volonté, Cinzia, Popoli, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933594/
https://www.ncbi.nlm.nih.gov/pubmed/33679392
http://dx.doi.org/10.3389/fphar.2020.633861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933594/
https://www.ncbi.nlm.nih.gov/pubmed/33679392
http://dx.doi.org/10.3389/fphar.2020.633861

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