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AhR Ligands Differentially Regulate miRNA-132 Which Targets HMGB1 and to Control the Differentiation of Tregs and Th-17 Cells During Delayed-Type Hypersensitivity Response

Aryl hydrocarbon receptor (AhR), is a transcription factor and an environmental sensor that has been shown to regulate T cell differentiation. Interestingly, AhR ligands exert varying effects from suppression to exacerbation of inflammation through induction of Tregs and Th-17 cells, respectively. I...

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Detalles Bibliográficos
Autores principales: Abdulla, Osama A., Neamah, Wurood, Sultan, Muthanna, Chatterjee, Saurabh, Singh, Narendra, Nagarkatti, Mitzi, Nagarkatti, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933657/
https://www.ncbi.nlm.nih.gov/pubmed/33679792
http://dx.doi.org/10.3389/fimmu.2021.635903