Cargando…

Assessing POR and CYB5R1 oxidoreductase-mediated oxidative rupture of PUFA in liposomes

Lipid peroxidation of polyunsaturated fatty acid (PUFA) phospholipids induces necrotic cell death through compromised cell membrane integrity during ferroptosis. We established assays to investigate oxidoreductase-mediated oxidative rupture, specifically via NADPH-cytochrome P450 reductase (POR) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Bo, Ai, Youwei, Zhang, Zhiyuan, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933802/
https://www.ncbi.nlm.nih.gov/pubmed/33718888
http://dx.doi.org/10.1016/j.xpro.2021.100360