A modified screening strategy for Lynch syndrome among MLH1-deficient CRCs: Analysis from consecutive Chinese patients in a single center

BACKGROUND: The low prevalence of the BRAF V600E mutation in colorectal cancers (CRCs) in Chinese populations has stimulated concern about the efficacy of BRAF mutation analysis for Lynch syndrome (LS) screening. METHODS: In total, 169 of 4104 consecutive CRC patients with absent MLH1 staining were...

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Detalles Bibliográficos
Autores principales: Wang, Wenmiao, Ying, Jianming, Shi, Susheng, Ye, Qiurong, Zou, Shuangmei, Dong, Lin, Lyu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933804/
https://www.ncbi.nlm.nih.gov/pubmed/33676177
http://dx.doi.org/10.1016/j.tranon.2021.101049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933804/
https://www.ncbi.nlm.nih.gov/pubmed/33676177
http://dx.doi.org/10.1016/j.tranon.2021.101049

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