Cargando…

Dental pulp–derived stem cells inhibit osteoclast differentiation by secreting osteoprotegerin and deactivating AKT signalling in myeloid cells

Osteoclasts (OCs) differentiate from the monocyte/macrophage lineage, critically regulate bone resorption and remodelling in both homeostasis and pathology. Various immune and non‐immune cells help initiating activation of myeloid cells for differentiation, whereas hyper‐activation leads to pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanji, Suman, Sarkar, Ripon, Pramanik, Asmita, Kshirsagar, Sudhir, Greene, Carl J., Das, Hiranmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933945/
https://www.ncbi.nlm.nih.gov/pubmed/33511706
http://dx.doi.org/10.1111/jcmm.16071