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Dental pulp–derived stem cells inhibit osteoclast differentiation by secreting osteoprotegerin and deactivating AKT signalling in myeloid cells
Osteoclasts (OCs) differentiate from the monocyte/macrophage lineage, critically regulate bone resorption and remodelling in both homeostasis and pathology. Various immune and non‐immune cells help initiating activation of myeloid cells for differentiation, whereas hyper‐activation leads to pathogen...
Autores principales: | Kanji, Suman, Sarkar, Ripon, Pramanik, Asmita, Kshirsagar, Sudhir, Greene, Carl J., Das, Hiranmoy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933945/ https://www.ncbi.nlm.nih.gov/pubmed/33511706 http://dx.doi.org/10.1111/jcmm.16071 |
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