Critical amino acids in the TM2 of EAAT2 are essential for membrane‐bound localization, substrate binding, transporter function and anion currents

Excitatory amino acid transporter 2 (EAAT2), the gene of which is known as solute carrier family 1 member 2 (SLC1A2), is an important membrane‐bound transporter that mediates approximately 90% of the transport and clearance of l‐glutamate at synapses in the central nervous system (CNS). Transmembran...

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Detalles Bibliográficos
Autores principales: Mai, Dongmei, Chen, Rongqing, Wang, Ji, Zheng, Jiawei, Zhang, Xiuping, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933967/
https://www.ncbi.nlm.nih.gov/pubmed/33523598
http://dx.doi.org/10.1111/jcmm.16212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933967/
https://www.ncbi.nlm.nih.gov/pubmed/33523598
http://dx.doi.org/10.1111/jcmm.16212

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