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Critical amino acids in the TM2 of EAAT2 are essential for membrane‐bound localization, substrate binding, transporter function and anion currents
Excitatory amino acid transporter 2 (EAAT2), the gene of which is known as solute carrier family 1 member 2 (SLC1A2), is an important membrane‐bound transporter that mediates approximately 90% of the transport and clearance of l‐glutamate at synapses in the central nervous system (CNS). Transmembran...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933967/ https://www.ncbi.nlm.nih.gov/pubmed/33523598 http://dx.doi.org/10.1111/jcmm.16212 |