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DNA methylation‐mediated silencing of microRNA‐204 enhances T cell acute lymphoblastic leukemia by up‐regulating MMP‐2 and MMP‐9 via NF‐κB

T cell acute lymphoblastic leukaemia (T‐ALL) is a highly aggressive haematological cancer of the bone marrow. The abnormal expression of microRNAs (miRNAs) is reportedly involved in T‐ALL development and progression. Thus, we aimed to decipher the involvement of miR‐204 silencing mediated by DNA met...

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Detalles Bibliográficos
Autores principales: Lin, Congmeng, Chen, Dabing, Xiao, Tingting, Lin, Dandan, Lin, Dayi, Lin, Luhui, Zhu, Haojie, Xu, Jingjing, Huang, Wenwen, Yang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7933971/
https://www.ncbi.nlm.nih.gov/pubmed/33566449
http://dx.doi.org/10.1111/jcmm.15896