Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice

Background: Targeting long-lasting insulins to the liver may improve metabolic alterations that are not corrected with current insulin replacement therapies. However, insulin is only able to promote lipogenesis but not to block gluconeogenesis in the insulin-resistant liver, exacerbating liver steat...

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Detalles Bibliográficos
Autores principales: Ardaiz, Nuria, Gomar, Celia, Vasquez, Marcos, Tenesaca, Shirley, Fernandez-Sendin, Myriam, Di Trani, Claudia Augusta, Belsué, Virginia, Escalada, Javier, Werner, Ulrich, Tennagels, Norbert, Berraondo, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934061/
https://www.ncbi.nlm.nih.gov/pubmed/33679386
http://dx.doi.org/10.3389/fphar.2020.591293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934061/
https://www.ncbi.nlm.nih.gov/pubmed/33679386
http://dx.doi.org/10.3389/fphar.2020.591293

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