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Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1

Bcl2-like-10 (Bcl2l10) has both oncogenic and tumor suppressor functions depending on the type of cancer. It has been previously demonstrated that the suppression of Bcl2l10 in ovarian cancer SKOV3 and A2780 cells causes cell cycle arrest and enhances cell proliferation, indicating that Bcl2l10 is a...

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Detalles Bibliográficos
Autores principales: Lee, Su-Yeon, Kwon, Jinie, Lee, Kyung-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934226/
https://www.ncbi.nlm.nih.gov/pubmed/33649794
http://dx.doi.org/10.3892/or.2021.7998