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TGF-β-induced α-SMA expression is mediated by C/EBPβ acetylation in human alveolar epithelial cells

BACKGROUND: Although the morbidity and mortality rates associated with idiopathic pulmonary fibrosis (IPF) are high, there is still lack of powerful and precise therapeutic options for IPF. OBJECT: Through in vitro model, this study sought to determine whether binding of acetylated CCAAT/enhancer bi...

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Detalles Bibliográficos
Autores principales: Ding, Hui, Chen, Jinjun, Qin, Jingping, Chen, Ruhua, Yi, Zili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934236/
https://www.ncbi.nlm.nih.gov/pubmed/33663392
http://dx.doi.org/10.1186/s10020-021-00283-6