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Challenges of applying multicellular tumor spheroids in preclinical phase

The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the heterogeneou...

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Detalles Bibliográficos
Autores principales: Han, Se Jik, Kwon, Sangwoo, Kim, Kyung Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934264/
https://www.ncbi.nlm.nih.gov/pubmed/33663530
http://dx.doi.org/10.1186/s12935-021-01853-8