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Hypermethylation of heparanase 2 promotes colorectal cancer proliferation and is associated with poor prognosis
BACKGROUND: The epigenetic abnormality of tumor-associated genes contributes to the pathogenesis of colorectal carcinoma (CRC). However, methylation in colorectal cancer is still poorly characterized. METHOD: By integration of DNA methylation data from the GEO database and gene expression data from...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934273/ https://www.ncbi.nlm.nih.gov/pubmed/33663522 http://dx.doi.org/10.1186/s12967-021-02770-0 |