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Hypermethylation of heparanase 2 promotes colorectal cancer proliferation and is associated with poor prognosis

BACKGROUND: The epigenetic abnormality of tumor-associated genes contributes to the pathogenesis of colorectal carcinoma (CRC). However, methylation in colorectal cancer is still poorly characterized. METHOD: By integration of DNA methylation data from the GEO database and gene expression data from...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Xu, Chenxin, Shi, Chen, Zhang, Junying, Qian, Ting, Wang, Zhuo, Ma, Rong, Wu, Jianzhong, Jiang, Feng, Feng, Jifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934273/ https://www.ncbi.nlm.nih.gov/pubmed/33663522 http://dx.doi.org/10.1186/s12967-021-02770-0

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