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Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model

BACKGROUND: Patients with metastatic HER2/neu-positive (HER2/neu +) breast cancer (BC) often experience treatment resistance, disease recurrences and metastases. Thus, new approaches for improving the treatment of HER2/neu + BC to prevent metastatic dissemination are urgently needed. Our previous st...

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Detalles Bibliográficos
Autores principales: Li, Wende, Li, Sen, Chen, Ivy X., Liu, Yujiao, Ramjiawan, Rakesh R., Leung, Chi-Ho, Gerweck, Leo E., Fukumura, Dai, Loeffler, Jay S., Jain, Rakesh K., Duda, Dan G., Huang, Peigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934382/
https://www.ncbi.nlm.nih.gov/pubmed/33663521
http://dx.doi.org/10.1186/s13014-021-01775-9