Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients

BACKGROUND: Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the utility of therapeutic drug monitoring (TDM), and to propose alternate dosing...

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Detalles Bibliográficos
Autores principales: Kawasuji, Hitoshi, Tsuji, Yasuhiro, Ogami, Chika, Kimoto, Kou, Ueno, Akitoshi, Miyajima, Yuki, Kawago, Koyomi, Sakamaki, Ippei, Yamamoto, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934392/
https://www.ncbi.nlm.nih.gov/pubmed/33663616
http://dx.doi.org/10.1186/s40360-021-00479-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934392/
https://www.ncbi.nlm.nih.gov/pubmed/33663616
http://dx.doi.org/10.1186/s40360-021-00479-w

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