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Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients
BACKGROUND: Linezolid is administered as a fixed dose to all patients despite evidence of overexposure and thrombocytopenia in renal impairment. The aims of this study were to evaluate the risk of thrombocytopenia and the utility of therapeutic drug monitoring (TDM), and to propose alternate dosing...
Autores principales: | Kawasuji, Hitoshi, Tsuji, Yasuhiro, Ogami, Chika, Kimoto, Kou, Ueno, Akitoshi, Miyajima, Yuki, Kawago, Koyomi, Sakamaki, Ippei, Yamamoto, Yoshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934392/ https://www.ncbi.nlm.nih.gov/pubmed/33663616 http://dx.doi.org/10.1186/s40360-021-00479-w |
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