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Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension
OBJECTIVES: Pulmonary hypertension (PH) is a life-threatening progressive disease with high mortality in the elderly. However, the pathogenesis of PH has not been fully understood and there is no effective therapy to reverse the disease process. This study aims to determine whether cellular senescen...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934412/ https://www.ncbi.nlm.nih.gov/pubmed/33673825 http://dx.doi.org/10.1186/s12890-021-01439-0 |