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Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis

BACKGROUND: As a classic innate immunity pathway, Toll-like receptor 4 (TLR4) signaling has been intensively investigated for its function of pathogen recognition. The receptor is located not only on immune cells but also on sensory neurons and spinal glia. Recent studies revealed the involvement of...

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Detalles Bibliográficos
Autores principales: Su, Wenliang, Cui, Huan, Wu, Danning, Yu, Jiawen, Ma, Lulu, Zhang, Xiuhua, Huang, Yuguang, Ma, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934423/
https://www.ncbi.nlm.nih.gov/pubmed/33673857
http://dx.doi.org/10.1186/s12974-020-02066-y