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Undercarboxylated osteocalcin inhibits the early differentiation of osteoclast mediated by Gprc6a

Osteocalcin (OCN) was the most abundant noncollagen protein and considered as an endocrine factor. However, the functions of Undercarboxylated osteocalcin (ucOCN) on osteoclast and bone resorption are not well understood. In the present study, preosteoclast RAW264.7 cells and bone marrow mononuclear...

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Detalles Bibliográficos
Autores principales: Wang, Hailong, Li, Jinqiao, Xu, Zihan, Wu, Feng, Zhang, Hongyu, Yang, Chao, Chen, Jian, Ding, Bai, Sui, Xiukun, Guo, Zhifeng, Li, Yinghui, Dai, Zhongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934677/
https://www.ncbi.nlm.nih.gov/pubmed/33717684
http://dx.doi.org/10.7717/peerj.10898