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Synthesis of (Z)-3-[amino(phenyl)methylidene]-1,3-dihydro-2H-indol-2-ones using an Eschenmoser coupling reaction

A highly modular method for the synthesis of (Z)-3-[amino(phenyl/methyl)methylidene]-1,3-dihydro-2H-indol-2-ones starting from easily available 3-bromooxindoles or (2-oxoindolin-3-yl)triflate and thioacetamides or thiobenzamides is described. A series of 49 compounds, several of which have previousl...

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Detalles Bibliográficos
Autores principales: Marek, Lukáš, Kolman, Lukáš, Váňa, Jiří, Svoboda, Jan, Hanusek, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934781/
https://www.ncbi.nlm.nih.gov/pubmed/33727976
http://dx.doi.org/10.3762/bjoc.17.47