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The aryl hydrocarbon receptor regulates expression of mucosal trafficking receptor GPR15

GPR15 is a chemoattractant receptor that facilitates colon homing of regulatory and effector CD4(+) T cells in health and colitis. The molecular mechanisms that control GPR15 expression are not fully known. Here we report the presence of two highly conserved aryl hydrocarbon receptor (AHR) binding s...

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Detalles Bibliográficos
Autores principales: Swaminathan, Gayathri, Nguyen, Linh P., Namkoong, Hong, Pan, Junliang, Haileselassie, Yeneneh, Patel, Akshar, Ji, Allison R., Mikhail, David M., Dinh, Theresa Thanh, Singh, Harpriya, Liao, Bryce, Vázquez-Montesino, Luis M., Butcher, Eugene C., Habtezion, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934811/
https://www.ncbi.nlm.nih.gov/pubmed/33674764
http://dx.doi.org/10.1038/s41385-021-00390-x