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Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

Asymmetric cell division (ACD) enables the maintenance of a stem cell population while simultaneously generating differentiated progeny. Cancer stem cells (CSCs) undergo multiple modes of cell division during tumor expansion and in response to therapy, yet the functional consequences of these divisi...

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Detalles Bibliográficos
Autores principales: Hitomi, Masahiro, Chumakova, Anastasia P., Silver, Daniel J., Knudsen, Arnon M., Pontius, W. Dean, Murphy, Stephanie, Anand, Neha, Kristensen, Bjarne W., Lathia, Justin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934841/
https://www.ncbi.nlm.nih.gov/pubmed/33351787
http://dx.doi.org/10.1172/jci.insight.130510