Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa

Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these models, but whether it also could be rescued by Nrf2...

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Detalles Bibliográficos
Autores principales: Wu, David M., Ji, Xuke, Ivanchenko, Maryna V., Chung, Michelle, Piper, Mary, Rana, Parimal, Wang, Sean K., Xue, Yunlu, West, Emma, Zhao, Sophia R., Xu, Hongbin, Cicconet, Marcelo, Xiong, Wenjun, Cepko, Constance L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934854/
https://www.ncbi.nlm.nih.gov/pubmed/33491671
http://dx.doi.org/10.1172/jci.insight.145029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934854/
https://www.ncbi.nlm.nih.gov/pubmed/33491671
http://dx.doi.org/10.1172/jci.insight.145029

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