Trk agonist drugs rescue noise-induced hidden hearing loss

TrkB agonist drugs are shown here to have a significant effect on the regeneration of afferent cochlear synapses after noise-induced synaptopathy. The effects were consistent with regeneration of cochlear synapses that we observed in vitro after synaptic loss due to kainic acid–induced glutamate tox...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandez, Katharine A., Watabe, Takahisa, Tong, Mingjie, Meng, Xiankai, Tani, Kohsuke, Kujawa, Sharon G., Edge, Albert S.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934864/
https://www.ncbi.nlm.nih.gov/pubmed/33373328
http://dx.doi.org/10.1172/jci.insight.142572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934864/
https://www.ncbi.nlm.nih.gov/pubmed/33373328
http://dx.doi.org/10.1172/jci.insight.142572

Ejemplares similares