Cargando…
Trk agonist drugs rescue noise-induced hidden hearing loss
TrkB agonist drugs are shown here to have a significant effect on the regeneration of afferent cochlear synapses after noise-induced synaptopathy. The effects were consistent with regeneration of cochlear synapses that we observed in vitro after synaptic loss due to kainic acid–induced glutamate tox...
Autores principales: | Fernandez, Katharine A., Watabe, Takahisa, Tong, Mingjie, Meng, Xiankai, Tani, Kohsuke, Kujawa, Sharon G., Edge, Albert S.B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934864/ https://www.ncbi.nlm.nih.gov/pubmed/33373328 http://dx.doi.org/10.1172/jci.insight.142572 |
Ejemplares similares
-
An antibody to RGMa promotes regeneration of cochlear synapses after noise exposure
por: Nevoux, Jerome, et al.
Publicado: (2021) -
Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
por: Shi, Lijuan, et al.
Publicado: (2016) -
Coding deficits in hidden hearing loss induced by noise: the nature and impacts
por: Song, Qiang, et al.
Publicado: (2016) -
Hidden Hearing Loss Impacts the Neural Representation of Speech in Background Noise
por: Monaghan, Jessica J.M., et al.
Publicado: (2020) -
Noise-Induced Hearing Loss in Gerbil: Round Window Assays of Synapse Loss
por: Jeffers, Penelope W. C., et al.
Publicado: (2021)