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Intravenous allogeneic umbilical cord blood–derived mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa patients

BACKGROUND: Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding type VII collagen [C7]). In this phase I/IIa trial, we evaluated the safety and possible clinical efficacy of intravenous infusion of...

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Detalles Bibliográficos
Autores principales: Lee, Sang Eun, Lee, Seung-Ju, Kim, Song-Ee, Kim, Kinam, Cho, Boyoung, Roh, Kyounghwan, Kim, Soo-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934866/
https://www.ncbi.nlm.nih.gov/pubmed/33491668
http://dx.doi.org/10.1172/jci.insight.143606