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STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects

The pathogenesis of preeclampsia and other hypertensive disorders of pregnancy remains poorly defined despite the substantial burden of maternal and neonatal morbidity associated with these conditions. In particular, the role of genetic variants as determinants of disease susceptibility is understud...

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Detalles Bibliográficos
Autores principales: Parchem, Jacqueline G., Kanasaki, Keizo, Lee, Soo Bong, Kanasaki, Megumi, Yang, Joyce L., Xu, Yong, Earl, Kadeshia M., Keuls, Rachel A., Gattone, Vincent H., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934881/
https://www.ncbi.nlm.nih.gov/pubmed/33301424
http://dx.doi.org/10.1172/jci.insight.141588