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Restoration of type I interferon signaling in intrahepatically primed CD8(+) T cells promotes functional differentiation
Hepatitis B virus–specific (HBV-specific) CD8(+) T cells fail to acquire effector functions after priming in the liver, but the molecular basis for the dysfunction is poorly understood. By comparing the gene expression profile of intrahepatically primed, dysfunctional HBV-specific CD8(+) T cells wit...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934883/ https://www.ncbi.nlm.nih.gov/pubmed/33400688 http://dx.doi.org/10.1172/jci.insight.145761 |