A GRM7 mutation associated with developmental delay reduces mGlu(7) expression and produces neurological phenotypes

The metabotropic glutamate receptor 7 (mGlu(7)) is a G protein–coupled receptor that has been recently linked to neurodevelopmental disorders. This association is supported by the identification of GRM7 variants in patients with autism spectrum disorder, attention deficit hyperactivity disorder, and...

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Detalles Bibliográficos
Autores principales: Fisher, Nicole M., AlHashim, Aqeela, Buch, Aditi B., Badivuku, Hana, Samman, Manar M., Weiss, Kelly M., Cestero, Gabriela I., Does, Mark D., Rook, Jerri M., Lindsley, Craig W., Conn, P. Jeffrey, Gogliotti, Rocco G., Niswender, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934925/
https://www.ncbi.nlm.nih.gov/pubmed/33476302
http://dx.doi.org/10.1172/jci.insight.143324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934925/
https://www.ncbi.nlm.nih.gov/pubmed/33476302
http://dx.doi.org/10.1172/jci.insight.143324

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