A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance

Reestablishing an appropriate balance between T effector cells (Teff) and Tregs is essential for correcting autoimmunity. Multiple sclerosis (MS) is an immune-mediated chronic CNS disease characterized by neuroinflammation, demyelination, and neuronal degeneration, in which the Teff:Treg balance is...

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Detalles Bibliográficos
Autores principales: Aqel, Saba I., Yang, Xiaozhi, Kraus, Emma E., Song, Jinhua, Farinas, Marissa F., Zhao, Erin Y., Pei, Wei, Lovett-Racke, Amy E., Racke, Michael K., Li, Chenglong, Yang, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934926/
https://www.ncbi.nlm.nih.gov/pubmed/33411696
http://dx.doi.org/10.1172/jci.insight.142376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934926/
https://www.ncbi.nlm.nih.gov/pubmed/33411696
http://dx.doi.org/10.1172/jci.insight.142376

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