Intranasal immunization with peptide-based immunogenic complex enhances BCG vaccine efficacy in a murine model of tuberculosis

Prime-boost immunization strategies are required to control the global tuberculosis (TB) pandemic, which claims approximately 3 lives every minute. Here, we have generated an immunogenic complex against Mycobacterium tuberculosis (M.tb), consisting of promiscuous T cell epitopes (M.tb peptides) and...

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Detalles Bibliográficos
Autores principales: Kumar, Santosh, Bhaskar, Ashima, Patnaik, Gautam, Sharma, Chetan, Singh, Dhiraj Kumar, Kaushik, Sandeep Rai, Chaturvedi, Shivam, Das, Gobardhan, Dwivedi, Ved Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934935/
https://www.ncbi.nlm.nih.gov/pubmed/33444288
http://dx.doi.org/10.1172/jci.insight.145228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934935/
https://www.ncbi.nlm.nih.gov/pubmed/33444288
http://dx.doi.org/10.1172/jci.insight.145228

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