Glucagon receptor signaling regulates weight loss via central KLB receptor complexes

Glucagon regulates glucose and lipid metabolism and promotes weight loss. Thus, therapeutics stimulating glucagon receptor (GCGR) signaling are promising for obesity treatment; however, the underlying mechanism(s) have yet to be fully elucidated. We previously identified that hepatic GCGR signaling...

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Detalles Bibliográficos
Autores principales: Nason, Shelly R., Antipenko, Jessica, Presedo, Natalie, Cunningham, Stephen E., Pierre, Tanya H., Kim, Teayoun, Paul, Jodi R., Holleman, Cassie, Young, Martin E., Gamble, Karen L., Finan, Brian, DiMarchi, Richard, Hunter, Chad S., Kharitonenkov, Alexei, Habegger, Kirk M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934938/
https://www.ncbi.nlm.nih.gov/pubmed/33411693
http://dx.doi.org/10.1172/jci.insight.141323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934938/
https://www.ncbi.nlm.nih.gov/pubmed/33411693
http://dx.doi.org/10.1172/jci.insight.141323

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