Epithelial IL-33 appropriates exosome trafficking for secretion in chronic airway disease

IL-33 is a key mediator of chronic airway disease driven by type 2 immune pathways, yet the nonclassical secretory mechanism for this cytokine remains undefined. We performed a comprehensive analysis in human airway epithelial cells, which revealed that tonic IL-33 secretion is dependent on the cera...

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Detalles Bibliográficos
Autores principales: Katz-Kiriakos, Ella, Steinberg, Deborah F., Kluender, Colin E., Osorio, Omar A., Newsom-Stewart, Catie, Baronia, Arjun, Byers, Derek E., Holtzman, Michael J., Katafiasz, Dawn, Bailey, Kristina L., Brody, Steven L., Miller, Mark J., Alexander-Brett, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934940/
https://www.ncbi.nlm.nih.gov/pubmed/33507882
http://dx.doi.org/10.1172/jci.insight.136166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7934940/
https://www.ncbi.nlm.nih.gov/pubmed/33507882
http://dx.doi.org/10.1172/jci.insight.136166

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