A survival of the fittest strategy for the selection of genotypes by which drug responders and non-responders can be predicted in small groups

Phenotype Prediction Scores (PPS) might be powerful tools to predict traits or the efficacy of treatments based on combinations of Single-Nucleotide Polymorphism (SNPs) in large samples. We developed a novel method to produce PPS models for small samples sizes. The set of SNPs is first filtered on t...

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Detalles Bibliográficos
Autores principales: Höhle, Daniël, van Rooij, Kim, Bloemers, Jos, Pfaus, James G., Michiels, Frits, Janssen, Paddy, Claassen, Eric, Tuiten, Adriaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935233/
https://www.ncbi.nlm.nih.gov/pubmed/33667227
http://dx.doi.org/10.1371/journal.pone.0246828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935233/
https://www.ncbi.nlm.nih.gov/pubmed/33667227
http://dx.doi.org/10.1371/journal.pone.0246828

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