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A survival of the fittest strategy for the selection of genotypes by which drug responders and non-responders can be predicted in small groups
Phenotype Prediction Scores (PPS) might be powerful tools to predict traits or the efficacy of treatments based on combinations of Single-Nucleotide Polymorphism (SNPs) in large samples. We developed a novel method to produce PPS models for small samples sizes. The set of SNPs is first filtered on t...
Autores principales: | Höhle, Daniël, van Rooij, Kim, Bloemers, Jos, Pfaus, James G., Michiels, Frits, Janssen, Paddy, Claassen, Eric, Tuiten, Adriaan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935233/ https://www.ncbi.nlm.nih.gov/pubmed/33667227 http://dx.doi.org/10.1371/journal.pone.0246828 |
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