Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity

Morbilliviruses, such as measles virus (MeV) and canine distemper virus (CDV), are highly infectious members of the paramyxovirus family. MeV is responsible for major morbidity and mortality in non-vaccinated populations. ERDRP-0519, a pan-morbillivirus small molecule inhibitor for the treatment of...

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Detalles Bibliográficos
Autores principales: Cox, Robert M., Sourimant, Julien, Govindarajan, Mugunthan, Natchus, Michael G., Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935272/
https://www.ncbi.nlm.nih.gov/pubmed/33621266
http://dx.doi.org/10.1371/journal.ppat.1009371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935272/
https://www.ncbi.nlm.nih.gov/pubmed/33621266
http://dx.doi.org/10.1371/journal.ppat.1009371

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